liver dysfunction

Clinical Study on Liver Dysfunction Caused by Anti-tuberculosis Drugs Alone or Combined with Anisodamine

单用抗结核药与并用山莨菪碱致肝损害的临床对照试验

Objective: To observe changes in liver function in the early stage after thermal injury and potential role of hepatic sinusoid endothelial cells ( SEC) in development of liver dysfunction.

目的：观察大鼠烫伤后早期肝功能变化及肝窦内皮细胞（SEC）在其中的作用。

The advanced patients often possess severe jaundice, severe liver dysfunction, biliary cirrhosis, portal hypertension.

晚期病人常有重度黄疸 、 严重肝功能损害 、 胆汁性肝硬变 、 门静脉高压症的表现.

Portal hypertension, splanchnic vasodilatation, liver insufficiency, and cardiovascular dysfunction are major pathophysiological hallmarks.

病理改变包括门静脉高压, 脾功能亢进, 肝功能恶化,心功能下降.

Conclusion: CDCA can damage mitochondrial membrane structure and result in liver dysfunction.

结论: CDCA破坏线粒体膜和引起肝功能减退.